Route

Des Moines to Myrtle Beach: what the flight costs

In the last 60 days we checked this route 2 times. The typical round trip was $680 per person and the lowest $546, taxes and fees included.

Per person
Lowest seen$546
Typical (median)$680
Price checks, 60 days2

Every fare we found in the last 30 days

CheckedTrip datesPer personAirlineStopsDurationSource
Oct 15, 2026Oct 30–Nov 1, 2026$546G4 + MXwith a stop22h 35mKiwi.com
Oct 15, 2026Oct 23–25, 2026$813G4 + MXwith a stop22h 35mKiwi.com

About Myrtle Beach

Myrtle Beach is the Grand Strand, sixty miles of Atlantic sand lined with resorts, golf courses, mini-golf and family entertainment.

Myrtle Beach from every city: when to go, where to stay, what to do

Questions about Des Moines to Myrtle Beach

What does a round trip from Des Moines to Myrtle Beach usually cost?

Over the last 60 days the typical price we found was $680 per person, taxes and fees included, across 2 checks; the lowest was $546.

When is the best time to fly from Des Moines to Myrtle Beach?

Myrtle Beach is at its best in May, June, September and October. Avoid December, January, February: Cool, grey winter with many attractions closed

Do I need a passport to fly from Des Moines to Myrtle Beach?

No passport needed for travelers from the United States: a government photo ID is enough for Myrtle Beach.