The best trips from Des Moines, from $335
Des Moines, IA flies out of Des Moines International (DSM). This week's picks start at $335 per person, round trip, taxes and fees included. Over the last 30 days the cheapest routes we priced from Des Moines were Orlando (from $315), Los Angeles (from $335), Las Vegas (from $445).
5 trips from Des Moines found this week · last one 33 min ago · next search in 01:14 · New trips from Des Moines land here as our bot finds them.
Our best picks from Des Moines right now
Prices per person, round trip, taxes and fees included.
$470 per person, round trip, taxes and fees included
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$656 $558 per person, round trip, taxes and fees included You save $98 (15%)
the typical fare on this route
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$454 $335 per person, round trip, taxes and fees included You save $119 (26%)
the typical fare on this route
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Most loved from Des Moines
Ranked by real clicks, hearts and shares in the last 7 days.
$454 $335 per person, round trip, taxes and fees included You save $119 (26%)
the typical fare on this route
$656 $558 per person, round trip, taxes and fees included You save $98 (15%)
the typical fare on this route
$470 per person, round trip, taxes and fees included
Also priced this week from Des Moines
The other finalists of the last refresh, cheapest fare we found per person.
| Destination | Dates | From | Nonstop |
|---|---|---|---|
| Orlando | Nov 14–21, 2026 | $315 | no |
| Phoenix & Scottsdale | Nov 14–21, 2026 | $558 | no |
| Sedona | Nov 14–21, 2026 | $558 | no |
| Asheville | Oct 23–25, 2026 | $617 | no |
| San Diego | Oct 23–25, 2026 | $632 | no |
| Mexico City | Nov 14–21, 2026 | $649 | no |
| Chicago | Oct 23–25, 2026 | $651 | yes |
| Honolulu & Oahu | Nov 14–21, 2026 | $705 | no |
| Cancún | Nov 14–21, 2026 | $807 | no |
| Cozumel | Nov 14–21, 2026 | $814 | no |
| Great Smoky Mountains | Oct 23–25, 2026 | $815 | no |
| Aruba | Nov 14–21, 2026 | $827 | no |
Cheapest routes from Des Moines, last 30 days
| Destination | Lowest | Typical | Checks |
|---|---|---|---|
| Orlando | $315 | $535 | 11 |
| Los Angeles | $335 | $454 | 8 · nonstop seen |
| Las Vegas | $445 | $475 | 9 · nonstop seen |
| Napa & Sonoma | $552 | $656 | 6 |
| Phoenix & Scottsdale | $558 | $558 | 1 |
| Sedona | $558 | $558 | 1 |
| Asheville | $617 | $708 | 2 |
| San Diego | $632 | $737 | 5 |
| Mexico City | $649 | $722 | 2 |
| Chicago | $651 | $651 | 3 · nonstop seen |
| Honolulu & Oahu | $705 | $829 | 2 |
| Cancún | $807 | $811 | 2 |
| Cozumel | $814 | $814 | 1 |
| Great Smoky Mountains | $815 | $815 | 3 |
| Aruba | $827 | $827 | 2 |
More trips from Des Moines
Every other trip page from Des Moines still ahead of its date.
- Las Vegas, Oct 23–25, 2026 from $445 Just found
- Kyoto & Osaka, Nov 14–23, 2026 from $1,596 Just found
Questions about flying from Des Moines
Which airports do the trips from Des Moines use?
Des Moines International (DSM). Fares are the cheapest round trip we found across them for the exact dates, per person, taxes and fees included.
How often do the Des Moines picks change?
Around the clock: our search runs every few minutes across the cities and new finds from Des Moines land on this page as they are published. A pick stays until its departure date, then moves to the archive with the price it had.
What are the cheapest places to fly from Des Moines right now?
In the last 30 days: Orlando from $315, Los Angeles from $335, Las Vegas from $445, Napa & Sonoma from $552, Phoenix & Scottsdale from $558, per person round trip.
Can I ask for a specific trip?
Yes. Use the Ask box: say the destination or the kind of trip and the dates, and a page with live prices appears under Des Moines within a few minutes.